M-Biotech's biosensor represents a new milestone
in glucose biosensor technology. M-Biotech's patented design
allows us to manufacture inexpensive yet highly durable sensors
for the continuous monitoring of blood glucose levels.
Our miniature design enables minimally invasive implantation
for painless and convenient monitoring. The key feature of our
efficient Glucose Biosensor is the combination of a glucose-sensitive
hydrogel and a miniature pressure sensor. Glucose-responsive
hydrogels are biocompatible materials that either swell or contract
when the glucose concentrations change in the body fluid surrounding
the hydrogel.
The Hydrogel
M-Biotech's hydrogel materials swell reversibly and to varying
degrees in response to specific concentrations of certain solutes.
This swelling corresponds to the amount of force that the gel
exerts on a pressure sensing diaphragm. The deflection of the
diaphragm is measured by means of a piezoresistive bridge and
the deflection provided as a change in voltage. Thus the various
amounts of force applied by the swellable hydrogel can be measured
as changes in voltage. The gels can be functionalized to swell
in response to concentration changes of protons, glucose and
salts in solution. We have a number of projects underway to
design gels that will swell preferentially in the presence of
various types and families of soluble factors.
